Anticorps Recombinant de lapin anti-BLIMP1/PRDM1

BLIMP1/PRDM1 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242030B1

N° de cat : 84625-3-PBS

Synonymes

BLIMP1, PRDM1, 242030B1, BLIMP 1, PRDI BF1

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Galerie de données de validation

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  WB analysis using 84625-3-RR (same clone as 84625-3-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 84625-3-RR (BLIMP1/PRDM1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84625-3-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 84625-3-RR (same clone as 84625-3-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using BLIMP1/PRDM1 antibody (84625-3-RR, Clone: 242030B1 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84625-3-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 84625-3-RR (same clone as 84625-3-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A549 cells using BLIMP1/PRDM1 antibody (84625-3-RR, Clone: 242030B1 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84625-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84625-3-PBS cible BLIMP1/PRDM1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: BLIMP1/PRDM1 Protéine recombinante Eg2625
• Nom complet: PR domain containing 1, with ZNF domain
• Masse moléculaire calculée: 92 kDa
• Poids moléculaire observé: 96-110 kDa
• Numéro d’acquisition GenBank: NM_001198.3
• Symbole du gène: PRDM1
• Identification du gène (NCBI): 639
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BLIMP1(B lymphocyte-induced maturation protein 1), also known as PRDM1(PR domain zinc finger protein 1), is an evolutionarily conserved transcriptional regulator originally described as a repressor of gene transcription(PMID: 35154079). BLIMP1/PRDM1 is widely expressed in multiple cell types including B lymphocytes, T lymphocytes, mammary luminal progenitor cells and skin epithelial cells. BLIMP1/PRDM1 is a master regulator of terminal B cell differentiation and may also function as a tumor suppressor in the pathogenesis of DLBCL, where it is frequently inactivated by mutations and deletions.

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