- Phare
- Validé par KD/KO
Anticorps Polyclonal de lapin anti-BMF
BMF Polyclonal Antibody for IP, Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain
Applications
IP, Indirect ELISA
Conjugaison
Non conjugué
N° de cat : 18298-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
18298-1-PBS cible BMF dans les applications de IP, Indirect ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | Peptide |
| Nom complet | Bcl2 modifying factor |
| Masse moléculaire calculée | 21 kDa |
| Poids moléculaire observé | 24 kDa |
| Numéro d’acquisition GenBank | BC069505 |
| Symbole du gène | BMF |
| Identification du gène (NCBI) | 90427 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
BMF belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities such as central regulators of apoptotic cell death. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. BMF is widely expressed in tissues such as pancreas, liver and kidney, and in hematopoietic tissues.
