Anticorps Polyclonal de lapin anti-BMPR1B

BMPR1B Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26696-1-PBS

Synonymes

BMP type 1B receptor, BMP type-1B receptor, BMPR 1B, BMPR-1B, Bone morphogenetic protein receptor type-1B

---

Galerie de données de validation

• 

  WB analysis using 26696-1-AP (same clone as 26696-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26696-1-AP (BMPR1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat ovary tissue slide using 26696-1-AP (BMPR1B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat ovary tissue slide using 26696-1-AP (BMPR1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

• 

  IF Staining of MCF-7 using 26696-1-AP (same clone as 26696-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using BMPR1B antibody (26696-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

26696-1-PBS cible BMPR1B dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BMPR1B Protéine recombinante Ag24902
• Nom complet: bone morphogenetic protein receptor, type IB
• Masse moléculaire calculée: 57 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC047773
• Symbole du gène: BMPR1B
• Identification du gène (NCBI): 658
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BMPR1B (Bone morphogenetic protein receptor type-1B) is also named as CDw293. BMPR1B belongs to the protein kinase superfamily. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. BMPR1B is receptor for BMP7/OP-1 and GDF5. BMPR1B Positively regulates chondrocyte differentiation through GDF5 interaction.

{{ptg:RelatedPrimaryAntibodies}}