Anticorps Polyclonal de lapin anti-BNIP2

BNIP2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10361-1-PBS

Synonymes

NIP2, BNIP 2, BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

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Galerie de données de validation

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  WB analysis using 10361-1-AP (same clone as 10361-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10361-1-AP (BNIP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10361-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 10361-1-AP (same clone as 10361-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using BNIP2 antibody (10361-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 10361-1-PBS in a different storage buffer formulation.

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  IF Staining of RAW 264.7 using 10361-1-AP (same clone as 10361-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed RAW 264.7 cells using BNIP2 antibody (10361-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10361-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10361-1-PBS cible BNIP2 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BNIP2 Protéine recombinante Ag0403
• Nom complet: BCL2/adenovirus E1B 19kDa interacting protein 2
• Masse moléculaire calculée: 36 kDa
• Poids moléculaire observé: 43 kDa
• Numéro d’acquisition GenBank: BC002461
• Symbole du gène: BNIP2
• Identification du gène (NCBI): 663
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2) is also named as PRKACN2. BNIP2 is developmentally regulated may suggest a role of this gene in those brain areas where the differentiation is orchestrated by estradiol. The expression of BNIP2 was inhibited by estradiol. BNIP2 is implicated in the suppression of cell death and interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. BNIP2 is highly expressed in patients with favorable neuroblastoma (NB) (PMID: 25611382).

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