Anticorps Polyclonal de lapin anti-BNP

BNP Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13299-1-PBS

Synonymes

Natriuretic peptides B, NPPB, BNP(3-29), BNP(2-31), BNP(1-30)

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Galerie de données de validation

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  IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 13299-1-AP (same clone as 13299-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using BNP antibody (13299-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13299-1-PBS cible BNP dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BNP Protéine recombinante Ag4039
• Nom complet: natriuretic peptide precursor B
• Masse moléculaire calculée: 134 aa, 15 kDa
• Numéro d’acquisition GenBank: BC025785
• Symbole du gène: BNP
• Identification du gène (NCBI): 4879
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.

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