Anticorps Polyclonal de lapin anti-BRD1/BRL

BRD1/BRL Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32452-1-PBS

Synonymes

BR140-like protein, BRD1, BRL, Bromodomain and PHD finger-containing protein 2, Bromodomain-containing protein 1

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Galerie de données de validation

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  WB analysis using 32452-1-AP (same clone as 32452-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32452-1-AP (BRD1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32452-1-PBS in a different storage buffer formulation.

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  IP experiment of Jurkat using 32452-1-AP (same clone as 32452-1-PBS)

  IP result of anti-BRD1/BRL (IP:32452-1-AP, 4ug; Detection:32452-1-AP 1:1000) with Jurkat cells lysate 1920 ug. This data was developed using the same antibody clone with 32452-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32452-1-PBS cible BRD1/BRL dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BRD1/BRL Protéine recombinante Ag37530
• Nom complet: bromodomain containing 1
• Masse moléculaire calculée: 120 kDa
• Poids moléculaire observé: 133 kDa
• Numéro d’acquisition GenBank: BC047508
• Symbole du gène: BRD1
• Identification du gène (NCBI): 23774
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BRD1, also known as BRL and BRPF2, plays a key role in chromatin recruitment to modulate histone acetylation and consequently gene transcription. It interacts with a range of epigenetic modifiers, including histone acetyltransferases KAT5 and KAT7, as well as the histone-lysine N-methyltransferase KMT5B (PMID: 29453316, 38383216). It has 2 isoforms with the molecular mass of 133 kDa and 120 kDa.

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