Anticorps Recombinant de lapin anti-BRD7

BRD7 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250776E3

N° de cat : 86176-1-PBS

Synonymes

BP75, Bromodomain-containing protein 7, CELTIX1, NAG4, Protein CELTIX 1

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Galerie de données de validation

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  WB analysis using 86176-1-RR (same clone as 86176-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86176-1-RR (BRD7 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86176-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86176-1-PBS cible BRD7 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: BRD7 Protéine recombinante Ag1461
• Nom complet: bromodomain containing 7
• Masse moléculaire calculée: 651 aa, 74 kDa
• Poids moléculaire observé: 74-78 kDa
• Numéro d’acquisition GenBank: BC050728
• Symbole du gène: BRD7
• Identification du gène (NCBI): 29117
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.

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