Anticorps Polyclonal de lapin anti-BRE

BRE Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11702-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 11702-1-AP (same clone as 11702-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11702-1-AP (BRE antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11702-1-PBS in a different storage buffer formulation.

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  IP experiment of HeLa using 11702-1-AP (same clone as 11702-1-PBS)

  IP result of anti-BRE (IP:11702-1-AP, 4ug; Detection:11702-1-AP 1:1000) with HeLa cells lysate 2320 ug. This data was developed using the same antibody clone with 11702-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 11702-1-AP (same clone as 11702-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 11702-1-AP (BRE antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11702-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 11702-1-AP (same clone as 11702-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 11702-1-AP (BRE antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11702-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11702-1-PBS cible BRE dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BRE Protéine recombinante Ag2256
• Nom complet: brain and reproductive organ-expressed (TNFRSF1A modulator)
• Masse moléculaire calculée: 383 aa, 44 kDa
• Poids moléculaire observé: 40-44 kDa
• Numéro d’acquisition GenBank: BC001251
• Symbole du gène: BRE
• Identification du gène (NCBI): 9577
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BRE, also named as BRCC45, is a death receptor-associated antiapoptotic protein, which is also involved in DNA-damage repair, and K63-specific deubiquitination. BRE and its XIAP-sustaining mechanism could represent novel targets for anti-cancer therapy. BRE may regulate TNF-alpha signaling through its interactions with TNFRSF1A. It plays a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. BRE gene has four isoforms with MW 42-47 kDa.

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