Anticorps Polyclonal de lapin anti-BRSK1

BRSK1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12673-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 12673-1-AP (same clone as 12673-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12673-1-AP (BRSK1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12673-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 12673-1-AP (same clone as 12673-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 12673-1-AP (BRSK1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12673-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 12673-1-AP (same clone as 12673-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 12673-1-AP (BRSK1 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12673-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 12673-1-AP (same clone as 12673-1-PBS)

  IP result of anti-BRSK1 (IP:12673-1-AP, 4ug; Detection:12673-1-AP 1:500) with mouse brain tissue lysate 3440ug. This data was developed using the same antibody clone with 12673-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary tumor using 12673-1-AP (same clone as 12673-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 12673-1-AP (BRSK1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 12673-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12673-1-PBS cible BRSK1 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BRSK1 Protéine recombinante Ag3357
• Nom complet: BR serine/threonine kinase 1
• Masse moléculaire calculée: 87 kDa
• Poids moléculaire observé: 85-90 kDa
• Numéro d’acquisition GenBank: BC016681
• Symbole du gène: BRSK1
• Identification du gène (NCBI): 84446
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BRSK1(Brain-specific serine/threonine-protein kinase 1) is also named as KIAA1811, SAD1, SADB and belongs to the SNF1 subfamily. BRSKs are crucial for establishing neuronal polarity, and BRSK1 has also been shown to regulate neurotransmitter release presynaptically. BRSK1 is a serine-threonine kinases specifically expressed in the brain, and activated by LKB1-mediated phosphorylation of a threonine residue at their T-loop. (PMID:22020259). It has 3 isoforms produced by alternative splicing.

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