Anticorps Polyclonal de lapin anti-BTG1

BTG1 Polyclonal Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 14879-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human thyroid cancer using 14879-1-AP

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 14879-1-AP (BTG1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human thyroid cancer using 14879-1-AP

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 14879-1-AP (BTG1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human lymphoma using 14879-1-AP (same clone as 14879-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 14879-1-AP (BTG1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14879-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lymphoma using 14879-1-AP (same clone as 14879-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 14879-1-AP (BTG1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14879-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14879-1-PBS cible BTG1 dans les applications de IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: BTG1 Protéine recombinante Ag6651
• Nom complet: B-cell translocation gene 1, anti-proliferative
• Masse moléculaire calculée: 19 kDa
• Numéro d’acquisition GenBank: BC064953
• Symbole du gène: BTG1
• Identification du gène (NCBI): 694
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BTG1 is a member of the TOB/BTG family of proteins known to inhibit cell proliferation and negatively regulate the cell cycle (PMID: 25017022). It is strongly expressed in quiescent cells (maximal in the G0/G1 phase) and down-regulated as the cells enter the growth cycle (PMID: 1373383). BTG1 protein is localized in cytoplasm and nucleus, and can interact with CAF1 and PRMT1 (PMID: 1113675, 9712883, 26622543). The aberration of BTG1 expression is associated with B-cell lymphocytic leukemia, and may serve as a diagnostic indicator and prognostic marker of thyroid carcinoma (PMID: 2069907, 25017022).

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