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Anticorps Polyclonal de lapin anti-BZRAP1

BZRAP1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28241-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of Neuro-2a cells using BZRAP1 Polyclonal antibody (28241-1-AP)

    WB analysis of Neuro-2a using 28241-1-AP (same clone as 28241-1-PBS)

    Neuro-2a cells were subjected to SDS PAGE followed by western blot with 28241-1-AP (BZRAP1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28241-1-PBS in a different storage buffer formulation.

Informations sur le produit

28241-1-PBS cible BZRAP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène BZRAP1 Protéine recombinante Ag28198
Nom complet benzodiazapine receptor (peripheral) associated protein 1
Masse moléculaire calculée 1857 aa, 200 kDa
Poids moléculaire observé 200-235 kDa
Numéro d’acquisition GenBankBC146852
Symbole du gène BZRAP1
Identification du gène (NCBI) 9256
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

BZRAP1, also named as TSPOAP1 and PBR-associated protein 1 (PRAX-1), is a cytoplasmic protein of 1857 residues. It plays a key role in inflammation, neuroinflammation, mental and metabolic diseases, and cancer. BZRAP1 predominantly expressed in the central nervous system, pituitary gland, and thymus, specially abundant in the CA1 subfield of the hippocampus. Tumor necrosis factor receptor 1 (TNFR1), vascular cell adhesion molecule 1 (VCAM1), cyclic AMP response element-binding protein 1 (CREB1), T-cell receptor (TCR), nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NLRP3), DNA-dependent protein kinase (DNA-PK or PRKDC), and mitochondrial permeability transition pore (mPTP) were the major interaction partners of BZRAP1 (PMID: 34212002).

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