Anticorps Monoclonal anti-Beta-2-Microglobulin

Beta-2-Microglobulin Monoclonal Antibody for WB, IHC, IF-P, ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, IHC, IF-P, ELISA

Conjugaison

Non conjugué

CloneNo.

1C3B7

N° de cat : 66207-1-PBS

Synonymes

B2M, 1C3B7, HDCMA22P, CDABP0092, Beta-2-microglobulin form pI 5.3

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Galerie de données de validation

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  WB analysis of Raji using 66207-1-Ig (same clone as 66207-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 66207-1-Ig (B2M Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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  WB analysis using 66207-1-Ig (same clone as 66207-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66207-1-Ig (Beta-2-Microglobulin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 66207-1-Ig (same clone as 66207-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66207-1-Ig (Beta-2-Microglobulin antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 66207-1-Ig (same clone as 66207-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66207-1-Ig (Beta-2-Microglobulin antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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  IHC staining of human renal cell carcinoma using 66207-1-Ig (same clone as 66207-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma tissue slide using 66207-1-Ig (B2M Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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  IHC staining of human renal cell carcinoma using 66207-1-Ig (same clone as 66207-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma tissue slide using 66207-1-Ig (B2M Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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  IF Staining of human prostate cancer using 66207-1-Ig (same clone as 66207-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human prostate cancer tissue using Beta-2-Microglobulin antibody (66207-1-Ig, Clone: 1C3B7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66207-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66207-1-PBS cible Beta-2-Microglobulin dans les applications de WB, IHC, IF-P, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: beta-2-microglobulin
• Masse moléculaire calculée: 14 kDa
• Poids moléculaire observé: 13 kDa
• Numéro d’acquisition GenBank: BC032589
• Symbole du gène: B2M
• Identification du gène (NCBI): 567
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.

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