Anticorps Recombinant de lapin anti-Beta-2-Microglobulin

Beta-2-Microglobulin Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241308F6

N° de cat : 83683-8-PBS

Synonymes

B2M, beta 2 microglobulin, beta 2-Microglobulin, Beta-2-microglobulin form pI 5.3, CDABP0092

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Galerie de données de validation

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  WB analysis using 83683-8-RR (same clone as 83683-8-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83683-8-RR (Beta-2-Microglobulin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83683-8-PBS in a different storage buffer formulation.

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  IF Staining of Jurkat using 83683-8-RR (same clone as 83683-8-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using Beta-2-Microglobulin antibody (83683-8-RR, Clone: 241308F6 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83683-8-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83683-8-RR

  Biolayer interferometry (BLl) kinetic assays of 83683-8-RR against Human Beta-2-Microglobulin were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83683-8-PBS cible Beta-2-Microglobulin dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Beta-2-Microglobulin Protéine recombinante Eg2284
• Nom complet: beta-2-microglobulin
• Masse moléculaire calculée: 119 aa, 14 kDa
• Poids moléculaire observé: 12 kDa
• Numéro d’acquisition GenBank: BC032589
• Symbole du gène: B2M
• Identification du gène (NCBI): 567
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions due to shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.

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