Anticorps Monoclonal anti-Beta Arrestin 1

• Phare
• Validé par KD/KO

Beta Arrestin 1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H8E4

N° de cat : 67580-1-PBS

Synonymes

ARRB1, ARR1, ARR 1, ARB2, ARB1

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Galerie de données de validation

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  WB analysis using 67580-1-Ig (same clone as 67580-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 67580-1-Ig (same clone as 67580-1-PBS)

  WB result of Beta Arrestin 1 antibody (67580-1-Ig; 1:8000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Beta Arrestin 1 transfected HepG2 cells. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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  WB analysis of NIH/3T3 using 67580-1-Ig (same clone as 67580-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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  WB analysis of human peripheral blood platelets using 67580-1-Ig (same clone as 67580-1-PBS)

  Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 67580-1-Ig (same clone as 67580-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 67580-1-Ig (Arrestin antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 67580-1-Ig (same clone as 67580-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67580-1-Ig (Beta Arrestin 1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67580-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67580-1-PBS cible Beta Arrestin 1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Beta Arrestin 1 Protéine recombinante Ag7504
• Nom complet: arrestin, beta 1
• Masse moléculaire calculée: 47 kDa
• Poids moléculaire observé: 45-55 kDa
• Numéro d’acquisition GenBank: BC003636
• Symbole du gène: Beta Arrestin 1
• Identification du gène (NCBI): 408
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

β-Arrestins (ARRBs), the best known regulators of G protein-coupled receptor signaling, are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including cell growth, apoptosis and immune responses. Overexpression of beta Arrestin 1 has been found in various cancers, indicating it as a potential therapeutic target for cancer treatment. Recently expression of ARRB1 in saliva has been identified as a candidate circadian biomarker. ARRB1 migrated as a doublet of two bands of 45 and 55 kDa (PMID:28947386).

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