Anticorps Recombinant de lapin anti-Beta Arrestin 2

Beta Arrestin 2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241470F8

N° de cat : 82780-6-PBS

Synonymes

ARRB2, β-Arrestin 2, 241470F8, ARB2, ARR2

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Galerie de données de validation

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  WB analysis using 82780-6-RR (same clone as 82780-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82780-6-RR (Beta Arrestin 2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82780-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82780-6-PBS

  Biolayer interferometry (BLl) kinetic assay of 82780-6-PBS against Human Beta Arrestin 2 was performed. The affinity constant is below 1 pM.

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  Affinity and Kinetic Characterization of 82780-6-RR

  Biolayer interferometry (BLl) kinetic assays of 82780-6-RR against Human Beta Arrestin 2 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

82780-6-PBS cible Beta Arrestin 2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Beta Arrestin 2 Protéine recombinante Ag0227
• Nom complet: arrestin, beta 2
• Masse moléculaire calculée: 46 kDa
• Poids moléculaire observé: 47-50 kDa
• Numéro d’acquisition GenBank: BC007427
• Symbole du gène: Beta Arrestin 2
• Identification du gène (NCBI): 409
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Beta Arrestin 2 is a member of arrestin/beta-arrestin protein family, which are expressed at high levels in the central nervous system (CNS) and play a critical role in the regulation of G-protein coupled receptors (GPCRs) including MOR. Beta Arrestin 2 is an adaptor protein that is important for the regulation of receptors belonging to both dopaminergic and opioid systems. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.

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