Anticorps Recombinant de lapin anti-C-Reactive Protein/CRP

C-Reactive Protein/CRP Recombinant Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

240759B8

N° de cat : 83741-3-PBS

Synonymes

PTX1, PTX 1, CRP, 240759B8

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Galerie de données de validation

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  WB analysis of rat liver using 83741-3-RR (same clone as 83741-3-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 83741-3-RR (C-Reactive Protein/CRP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83741-3-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 83741-3-RR (same clone as 83741-3-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 83741-3-RR (C-Reactive Protein/CRP antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83741-3-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 83741-3-RR (same clone as 83741-3-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 83741-3-RR (C-Reactive Protein/CRP antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83741-3-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83741-3-RR

  Biolayer interferometry (BLl) kinetic assays of 83741-3-RR against Rat Crp were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83741-3-PBS cible C-Reactive Protein/CRP dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons rat

• Réactivité: rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: C-reactive protein, pentraxin-related
• Masse moléculaire calculée: 25 kDa
• Poids moléculaire observé: 25 kDa
• Numéro d’acquisition GenBank: NM_017096.3
• Symbole du gène: Crp
• Identification du gène (NCBI): 25419
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein belonging to the pentraxin family. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.

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