Anticorps Polyclonal de lapin anti-C10orf88

C10orf88 Polyclonal Antibody for IHC, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

IHC, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26026-1-PBS

Synonymes

ATPase PAAT, EC:3.6.1.-, PAAT, Protein associated with ABC transporters

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Galerie de données de validation

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  IP experiment of SH-SY5Y using 26026-1-AP (same clone as 26026-1-PBS)

  IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with SH-SY5Y cells lysate 1920 ug. This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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  IP experiment of HEK-293 using 26026-1-AP (same clone as 26026-1-PBS)

  IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with HEK-293 cells lysate 1600 ug. This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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  IHC staining of rat pancreas using 26026-1-AP (same clone as 26026-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 26026-1-AP (C10orf88 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 26026-1-AP (same clone as 26026-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using C10orf88 antibody (26026-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26026-1-PBS cible C10orf88 dans les applications de IHC, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: C10orf88 Protéine recombinante Ag22971
• Nom complet: chromosome 10 open reading frame 88
• Masse moléculaire calculée: 445 aa, 49 kDa
• Poids moléculaire observé: 49 kDa
• Numéro d’acquisition GenBank: BC032645
• Symbole du gène: C10orf88
• Identification du gène (NCBI): 80007
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

C10orf88 (Chromosome 10 Open Reading Frame 88) is a mitochondria-localized protein that is thought to be associated with protein-binding activity of mitochondria and plays a role in mitochondrial dysfunction and metabolic diseases. Studies suggest that C10orf88 may be involved in cellular metabolism, cell cycle regulation, and maintenance of mitochondrial homeostasis. Its activity is closely related to ATP synthesis and oxidative phosphorylation in mitochondria, and may be affected by a variety of metabolic regulators (e.g., metformin, AICAR) and cell cycle regulators (e.g., rosavitine). In addition, inhibitors of C10orf88 (e.g., oryzanamycin, rotenone) modulate its activity by affecting ATP synthase and electron transport chain complex I in mitochondria.

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