Anticorps Polyclonal de lapin anti-C19orf63

C19orf63 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30844-1-PBS

Synonymes

EMC10, ER Membrane Protein Complex Subunit 10, Hematopoietic signal peptide-containing membrane domain-containing protein 1, HSM1, HSS1

---

Galerie de données de validation

• 

  WB analysis using 30844-1-AP (same clone as 30844-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30844-1-AP (C19orf63 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 30844-1-AP (same clone as 30844-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 30844-1-AP (C19orf63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 30844-1-AP (same clone as 30844-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 30844-1-AP (C19orf63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

30844-1-PBS cible C19orf63 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: C19orf63 Protéine recombinante Ag34064
• Nom complet: chromosome 19 open reading frame 63
• Poids moléculaire observé: 28 kDa
• Numéro d’acquisition GenBank: BC035001
• Symbole du gène: C19orf63
• Identification du gène (NCBI): 284361
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) is one of the key components of the highly conserved endoplasmic reticulum membrane protein complex (EMC). The core function of this complex is to act as an insertase and chaperone in the endoplasmic reticulum, assisting in the correct folding, assembly, and membrane integration of membrane proteins, and preventing the aggregation of misfolded proteins. Studies have shown that EMC10 plays a dual role in cells: within the cell, it ensures the biogenesis of important membrane proteins such as G protein-coupled receptors (GPCRs); moreover, it can be secreted outside the cell (referred to as sEMC10), where it acts as a novel signaling molecule to activate the hypothalamic-pituitary axis, regulating energy metabolism and body weight in the body, and is closely related to obesity and metabolic diseases.

{{ptg:RelatedPrimaryAntibodies}}