Anticorps Polyclonal de lapin anti-C1S

C1S Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14554-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human plasma using 14554-1-AP (same clone as 14554-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 14554-1-AP (C1S antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 14554-1-AP (same clone as 14554-1-PBS)

  rat plasma lysates were subjected to SDS PAGE followed by western blot with 14554-1-AP (C1S antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human plasma using 14554-1-AP (same clone as 14554-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 14554-1-AP (C1S antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14554-1-PBS cible C1S dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: C1S Protéine recombinante Ag5977
• Nom complet: complement component 1, s subcomponent
• Masse moléculaire calculée: 77 kDa
• Poids moléculaire observé: 88 kDa
• Numéro d’acquisition GenBank: BC056903
• Symbole du gène: C1S
• Identification du gène (NCBI): 716
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r activates C1s so that it can, in turn, activate C2 and C4. C1s is a glycoprotein of approximately 88 kDa, which is activated by cleavage into an A chain and a B chain.

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