Anticorps Polyclonal de lapin anti-C4orf32

C4orf32 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 33453-1-AP

Synonymes

FAM241A, Family With Sequence Similarity 241 Member A, Uncharacterized protein FAM241A

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Galerie de données de validation

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  WB analysis using 33453-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33453-1-AP (C4orf32 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu placentaire humain,

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

33453-1-AP cible C4orf32 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: C4orf32 Protéine recombinante Ag38764
• Nom complet: chromosome 4 open reading frame 32
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC022534
• Symbole du gène: C4orf32
• Identification du gène (NCBI): 132720
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The FAM241A protein, also known as C4orf32, is a key regulatory factor that is localized to the Golgi apparatus. It plays an important role in maintaining the structural integrity of the Golgi apparatus and is involved in processes such as protein glycosylation and vesicle transport. More importantly, FAM241A has been identified as a novel negative regulator of the Hippo signaling pathway. It directly binds to and inhibits the activity of the core kinases MST1/2, thereby relieving the suppression of the downstream effectors YAP/TAZ, promoting cell proliferation, and inhibiting apoptosis. Aberrant function of FAM241A is closely related to the occurrence and development of various human diseases, especially tumors, making it a highly promising target for basic research and clinical translation.

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