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Anticorps Polyclonal de lapin anti-C4orf32

C4orf32 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33453-1-PBS

Synonymes

FAM241A, Family With Sequence Similarity 241 Member A, Uncharacterized protein FAM241A

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using C4orf32 Polyclonal antibody (33453-1-AP)

    WB analysis using 33453-1-AP (same clone as 33453-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33453-1-AP (C4orf32 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33453-1-PBS in a different storage buffer formulation.

Informations sur le produit

33453-1-PBS cible C4orf32 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène C4orf32 Protéine recombinante Ag38764
Nom complet chromosome 4 open reading frame 32
Poids moléculaire observé20 kDa
Numéro d’acquisition GenBankBC022534
Symbole du gène C4orf32
Identification du gène (NCBI) 132720
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The FAM241A protein, also known as C4orf32, is a key regulatory factor that is localized to the Golgi apparatus. It plays an important role in maintaining the structural integrity of the Golgi apparatus and is involved in processes such as protein glycosylation and vesicle transport. More importantly, FAM241A has been identified as a novel negative regulator of the Hippo signaling pathway. It directly binds to and inhibits the activity of the core kinases MST1/2, thereby relieving the suppression of the downstream effectors YAP/TAZ, promoting cell proliferation, and inhibiting apoptosis. Aberrant function of FAM241A is closely related to the occurrence and development of various human diseases, especially tumors, making it a highly promising target for basic research and clinical translation.

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