Anticorps Polyclonal de lapin anti-C5

C5 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22492-1-PBS

Synonymes

C5, C5a, C5, C5b, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, Complement C5

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Galerie de données de validation

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  WB analysis using 22492-1-AP (same clone as 22492-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22492-1-AP (C5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22492-1-PBS in a different storage buffer formulation.

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  WB analysis using 22492-1-AP (same clone as 22492-1-PBS)

  rat plasma was subjected to SDS PAGE followed by western blot with 22492-1-AP (C5 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22492-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22492-1-PBS cible C5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: C5 Protéine recombinante Ag17882
• Nom complet: complement component 5
• Masse moléculaire calculée: 1676 aa, 188 kDa
• Poids moléculaire observé: 120 kDa, 70 kDa
• Numéro d’acquisition GenBank: BC113740
• Symbole du gène: C5
• Identification du gène (NCBI): 727
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The complement system is an important effector that bridges the innate and adaptive immune systems. The fifth component of complement, C5, is part of the complement cascade and plays an important role in inflammation and cell killing. It consists of disulfide-linked alpha and beta polypeptide chains but can be cleaved into two active peptides (C5a and C5b) by C5 convertases. Mutations and defects in C5 are associated with severe recurrent infections. (PMID: 20010915; PMID: 8011297; PMID: 6554279)

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