Anticorps Recombinant de lapin anti-C5AR1/CD88

C5AR1/CD88 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

APC Fluorescent Dye

CloneNo.

241712D4

N° de cat : APC-FcA98226

Synonymes

C5AR, C5AR1, C5A, C5a anaphylatoxin chemotactic receptor 1, C5a R

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Galerie de données de validation

• 

  FC experiment of human peripheral blood leukocytes using APC-FcA98226

  1x10^6 human peripheral blood leukocytes were surface stained with FcZero-rAb™ PE Anti-Human CD16, and 5 ul APC Anti-Human C5AR1/CD88 Rabbit RecAb (APC-FcA98226, Clone: 241712D4) or APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-FcA98226 cible C5AR1/CD88 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: C5AR1/CD88 Protéine recombinante Eg2185
• Nom complet: complement component 5a receptor 1
• Masse moléculaire calculée: 39kDa
• Numéro d’acquisition GenBank: NM_001736.4
• Symbole du gène: C5aR
• Identification du gène (NCBI): 728
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production.

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