Anticorps Polyclonal de lapin anti-Complement C6

Complement C6 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17239-1-PBS

Synonymes

C6, complement component 6, Complement component C6

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Galerie de données de validation

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  WB analysis of human blood using 17239-1-AP (same clone as 17239-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 17239-1-AP (C6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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  IP experiment of human plasma using 17239-1-AP (same clone as 17239-1-PBS)

  IP result of anti-Complement C6 (IP:17239-1-AP, 4ug; Detection:17239-1-AP 1:3000) with human plasma lysate 3200 ug. This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17239-1-AP (C6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17239-1-AP (C6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 17239-1-AP (C6 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 17239-1-AP (C6 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17239-1-PBS cible Complement C6 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Complement C6 Protéine recombinante Ag11083
• Nom complet: complement component 6
• Masse moléculaire calculée: 934 aa, 105 kDa
• Poids moléculaire observé: 105-120 kDa
• Numéro d’acquisition GenBank: BC035723
• Symbole du gène: C6
• Identification du gène (NCBI): 729
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.

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