Anticorps Polyclonal de lapin anti-G6B

G6B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26131-1-PBS

Synonymes

C6orf25, G6B-B, Megakaryocyte and platelet inhibitory receptor G6b, MPIG6B, NG31

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Galerie de données de validation

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  WB analysis using 26131-1-AP (same clone as 26131-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26131-1-AP (C6orf25 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26131-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26131-1-PBS cible G6B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: G6B Protéine recombinante Ag23442
• Nom complet: chromosome 6 open reading frame 25
• Poids moléculaire observé: 24-29 kDa
• Numéro d’acquisition GenBank: BC113719
• Symbole du gène: C6orf25
• Identification du gène (NCBI): 80739
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

C6orf25, also called G6B, is an inhibitory receptor expressed on the surface of platelets,and it acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PMID: 17311996; 12665801; 27743390). C6orf25 has seven isoforms. Isoform B is the only isoform to contain both a transmembrane region and 2 immunoreceptor tyrosine-based inhibitor motifs (ITIMs) and, thus, the only one which probably has a role of inhibitory receptor. Isoform A may be the activating counterpart of isoform B (PMID: 11544253).

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