Anticorps Recombinant de lapin anti-C8G

C8G Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242479G11

N° de cat : 85652-1-PBS

Synonymes

C8C

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Galerie de données de validation

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  WB analysis using 85652-1-RR (same clone as 85652-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85652-1-RR (C8G antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85652-1-PBS in a different storage buffer formulation.

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  WB analysis of human plasma using 85652-1-RR (same clone as 85652-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 85652-1-RR (C8G antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85652-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85652-1-PBS cible C8G dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: C8G Protéine recombinante Ag18261
• Nom complet: complement component 8, gamma polypeptide
• Masse moléculaire calculée: 202 aa, 22 kDa
• Poids moléculaire observé: 18-22 kDa
• Numéro d’acquisition GenBank: BC113626
• Symbole du gène: C8G
• Identification du gène (NCBI): 733
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The gamma chain of complement component 8 (C8G) is one of three different subunits (alpha, beta, and gamma) of the eighth complement component (C8), which is a component of the MAC (membrane attack complex) (PMID:33382892). Although the roles of C8A and C8B are directly associated with MAC formation, C8G is not essential in the assembly and activity of the MAC (PMID:11960635). Moreover, C8G was shown to inhibit neuroinflammation by interfering with the sphingosine-1-phosphate (S1P)-S1PR2 interaction (PMID:34149451).

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