Anticorps Polyclonal de lapin anti-CACNA2D2

• Phare
• Validé par KD/KO

CACNA2D2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22145-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of SH-SY5Y using 22145-1-AP (same clone as 22145-1-PBS)

  WB result of CACNA2D2 antibody (22145-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CACNA2D2 transfected SH-SY5Y cells. This data was developed using the same antibody clone with 22145-1-PBS in a different storage buffer formulation.

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  WB analysis using 22145-1-AP (same clone as 22145-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22145-1-AP (CACNA2D2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22145-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22145-1-PBS cible CACNA2D2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CACNA2D2 Protéine recombinante Ag17580
• Nom complet: calcium channel, voltage-dependent, alpha 2/delta subunit 2
• Masse moléculaire calculée: 1145 aa, 129 kDa
• Poids moléculaire observé: 100-112 kDa
• Numéro d’acquisition GenBank: BC152438
• Symbole du gène: CACNA2D2
• Identification du gène (NCBI): 9254
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2), also known as CASVDD. It is expected to be located in cell membrane. The protein is predominantly present in cerebellar cortex. Present in various lung tumor cell lines, while it is absent in normal lung (at protein level). Highly expressed in heart, lung, testis, pancreas and skeletal muscle. Also expressed in kidney, liver, placenta and brain (PMID: 10766861). The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (PMID: 15111129). The molecular weight of CACNA2D2 is 129 kDa, and it can recognize other isoforms, which can be cut into fragments.

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