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Anticorps Polyclonal de lapin anti-CACTIN

CACTIN Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32066-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using CACTIN Polyclonal antibody (32066-1-AP)

    WB analysis using 32066-1-AP (same clone as 32066-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32066-1-AP (CACTIN antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32066-1-PBS in a different storage buffer formulation.

Informations sur le produit

32066-1-PBS cible CACTIN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CACTIN Protéine recombinante Ag35645
Nom complet chromosome 19 open reading frame 29
Masse moléculaire calculée 108 kDa, 89 kDa
Poids moléculaire observé120 kDa
Numéro d’acquisition GenBankNM_021231
Symbole du gène C19orf29
Identification du gène (NCBI) 58509
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CACTIN plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (PubMed:28062851).CACTIN was reported to be involved in the regulation of innate immune response (PubMed:20829348). CACTIN acts as a negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (PubMed:20829348, PubMed:26363554). CACTIN contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (PubMed:20829348, PubMed:26363554). CACTIN has two isforms (89kDa and 108 kDa).

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