Anticorps Polyclonal de lapin anti-CALCA/Calcitonin

CALCA/Calcitonin Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22244-1-PBS

Synonymes

CALCA/CGRP, CALCA, Calcitonin, CALC1, Calcitonin gene-related peptide 1

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Galerie de données de validation

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  WB analysis using 22244-1-AP (same clone as 22244-1-PBS)

  TT cells were subjected to SDS PAGE followed by western blot with 22244-1-AP (CGRP antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22244-1-PBS in a different storage buffer formulation.

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  WB analysis of Transfected HEK-293 using 22244-1-AP (same clone as 22244-1-PBS)

  Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 22244-1-AP (CGRP antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22244-1-PBS in a different storage buffer formulation.

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  IP experiment of TT using 22244-1-AP (same clone as 22244-1-PBS)

  IP result of anti-CALCA/CGRP (IP:22244-1-AP, 4ug; Detection:22244-1-AP 1:600) with TT cells lysate 945 ug. This data was developed using the same antibody clone with 22244-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22244-1-PBS cible CALCA/Calcitonin dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CALCA/Calcitonin Protéine recombinante Ag17737
• Nom complet: Calcitonin
• Masse moléculaire calculée: 141 aa, 15 kDa
• Poids moléculaire observé: 14 kDa, 5 kDa
• Numéro d’acquisition GenBank: BC093753
• Symbole du gène: CALCA
• Identification du gène (NCBI): 796
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Calcitonin is a peptide hormone consisting of 32 amino acids, primarily synthesized by the parafollicular cells (C cells) of the human thyroid gland. It plays a crucial role in regulating calcium levels in the blood by decreasing them. Calcitonin opposes the actions of parathyroid hormone, which increases blood calcium levels. Calcitonin works through a G protein-coupled receptor, known as the calcitonin receptor, which predominantly transmits signals via the cAMP and PLC/IP3 pathways. Its primary physiological effects are on osteoclasts and the tubular epithelium of kidneys.

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