Anticorps Monoclonal anti-CALCA/Calcitonin

CALCA/Calcitonin Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

1A12A1

N° de cat : 68774-1-PBS

Synonymes

CALCA/CGRP, CALCA, Calcitonin, 1A12A1, CALC1

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Galerie de données de validation

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  WB analysis of TT using 68774-1-Ig (same clone as 68774-1-PBS)

  TT cells were subjected to SDS PAGE followed by western blot with 68774-1-Ig (CALCA/CGRP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68774-1-PBS in a different storage buffer formulation.

• 

  Sample test of MP50293-1

  Cytometric bead array in cell lysate using MP50293-1, CALCA Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68774-1-PBS. Detection antibody: 68774-2-PBS. Cell lysate: TT, HepG2.

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  IHC staining of human thyroid cancer using 68774-1-Ig (same clone as 68774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 68774-1-Ig (CALCA/CGRP antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 68774-1-Ig (same clone as 68774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 68774-1-Ig (CALCA/CGRP antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68774-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP50293-1

  Cytometric bead array standard curve of MP50293-1, CALCA Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68774-1-PBS. Detection antibody: 68774-2-PBS. Standard:Ag26141. Range: 0.781-100 ng/mL.

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Informations sur le produit

68774-1-PBS cible CALCA/Calcitonin dans les applications de WB, IHC, Cytometric bead array, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CALCA/Calcitonin Protéine recombinante Ag26141
• Nom complet: Calcitonin
• Masse moléculaire calculée: 141 aa, 15 kDa
• Poids moléculaire observé: 14 kDa
• Numéro d’acquisition GenBank: BC093753
• Symbole du gène: CALCA
• Identification du gène (NCBI): 796
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Calcitonin is a peptide hormone consisting of 32 amino acids, primarily synthesized by the parafollicular cells (C cells) of the human thyroid gland. It plays a crucial role in regulating calcium levels in the blood by decreasing them. Calcitonin opposes the actions of parathyroid hormone, which increases blood calcium levels. Calcitonin works through a G protein-coupled receptor, known as the calcitonin receptor, which predominantly transmits signals via the cAMP and PLC/IP3 pathways. Its primary physiological effects are on osteoclasts and the tubular epithelium of kidneys.

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