Anticorps Monoclonal anti-CAMK4

CAMK4 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1G7A7

N° de cat : 68452-1-PBS

Synonymes

CaM kinase GR, CaMK GR, CaMK IV, CAMK4

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Galerie de données de validation

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  WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68452-1-Ig (CAMK4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68452-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68452-1-PBS cible CAMK4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CAMK4 Protéine recombinante Ag33332
• Nom complet: calcium/calmodulin-dependent protein kinase IV
• Masse moléculaire calculée: 473 aa, 52 kDa
• Poids moléculaire observé: 56-65 kDa
• Numéro d’acquisition GenBank: BC025687
• Symbole du gène: CAMK4
• Identification du gène (NCBI): 814
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)

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