Anticorps Monoclonal anti-CBX2

CBX2 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1D3H3

N° de cat : 68244-1-PBS

Synonymes

SRXY5, M33, CDCA6, 1D3H3

---

Galerie de données de validation

• 

  WB analysis using 68244-1-Ig (same clone as 68244-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68244-1-Ig (CBX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68244-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HEK-293 using 68244-1-Ig (same clone as 68244-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HEK-293 cells using CBX2 antibody (68244-1-Ig, Clone: 1D3H3 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68244-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

68244-1-PBS cible CBX2 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CBX2 Protéine recombinante Ag8311
• Nom complet: chromobox homolog 2 (Pc class homolog, Drosophila)
• Masse moléculaire calculée: 56 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC004252
• Symbole du gène: CBX2
• Identification du gène (NCBI): 84733
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The chromobox homolog protein 2 (CBX2) is a critical component of the PRC1 complex involved in antiviral innate immunity, neuronal, and gonadal differentiation, axial patterning during embryonic development, cell proliferation, and senescence (PMID: 32870972). CBX2 has 2 isoforms with the molecular mass of 23 and 56 kDa. Sometimes higher molecular weight around 65-70 kDa can also be observed, which may be a modified variant of CBX2.

{{ptg:RelatedPrimaryAntibodies}}