Anticorps Recombinant de lapin anti-CCDC23

CCDC23 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230175B2

N° de cat : 82998-4-PBS

Synonymes

CCDC23, SVBP

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Galerie de données de validation

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  IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using CCDC23 antibody (82998-4-RR, Clone: 230175B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1).CL594-Phalloidin (red). This data was developed using the same antibody clone with 82998-4-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using CCDC23 antibody (82998-4-RR, Clone: 230175B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1).CL594-Phalloidin (red). This data was developed using the same antibody clone with 82998-4-PBS in a different storage buffer formulation.

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Informations sur le produit

82998-4-PBS cible CCDC23 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCDC23 Protéine recombinante Ag33650
• Nom complet: coiled-coil domain containing 23
• Numéro d’acquisition GenBank: BC029427
• Symbole du gène: CCDC23
• Identification du gène (NCBI): 374969
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCDC23 also known as SVBP is a small vasohibin-binding protein of 66 amino acids, and functions as a chaperone of VASH1 in vascular endothelial cells(PMID: 20736312). SVBP enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin(PMID: 29146869, 31171830). Mutations in SVBP cause Neurodevelopmental disorders with ataxia, hypotonia, and microcephaly (NEDAHM)(PMID: 30607023, 31363758).

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