Anticorps Polyclonal de lapin anti-CCDC85C

CCDC85C Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

Conjugaison

Non conjugué

N° de cat : 31200-1-PBS

Synonymes

FLJ22558

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Galerie de données de validation

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  WB analysis using 31200-1-AP (same clone as 31200-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31200-1-AP (CCDC85C antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31200-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31200-1-PBS cible CCDC85C dans les applications de et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CCDC85C Protéine recombinante Ag35157
• Nom complet: coiled-coil domain containing 85C
• Masse moléculaire calculée: 419 aa, 45 kDa
• Poids moléculaire observé: 45-50 kDa
• Numéro d’acquisition GenBank: NM_001144995
• Symbole du gène: CCDC85C
• Identification du gène (NCBI): 317762
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ccdc85c (coiled-coil domain containing 85c) is a gene encoding protein, which is located on human chromosome 14 (14q32.2) and belongs to the helical loop domain protein family. The protein is mainly expressed in the neuroepithelial cells of the lateral ventricle wall of the brain, especially at the top junction of radial glial cells. In addition, it is also expressed in a variety of monolayer epithelial cells, but not in stratified epithelial cells. CCDC85C is the pathogenic gene of hereditary hydrocephalus and subcortical endometriosis (often accompanied by cerebral hemorrhage). In CCDC85C gene knockout (KO) mice and rats, abnormal development of ventricular system was observed, resulting in hydrocephalus and cerebral hemorrhage (PMID: 37271245).

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