Anticorps Recombinant de lapin anti-CCL1

CCL1 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

250094D6

N° de cat : 98502-2-PBS

Synonymes

C-C motif chemokine 1, P500, Scya1, SIS-epsilon, Small-inducible cytokine A1

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98502-2-RR (same clone as 98502-2-PBS)

  1x10^6 HEK-293T cells or CCL1-transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse CCL1 Rabbit RecAb (98502-2-RR, Clone: 250094D6) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98502-2-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98502-2-RR (same clone as 98502-2-PBS)

  1x10^6 HEK-293T cells or CCL1-transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse CCL1 Rabbit RecAb (98502-2-RR, Clone: 250094D6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98502-2-PBS in a different storage buffer formulation.

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Informations sur le produit

98502-2-PBS cible CCL1 dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCL1 Protéine recombinante Eg3293
• Nom complet: chemokine (C-C motif) ligand 1
• Masse moléculaire calculée: 10KD
• Numéro d’acquisition GenBank: NM_011329.3
• Symbole du gène: Ccl1
• Identification du gène (NCBI): 20290
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CCL1, also known as I-309 in human or TCA-3 in mice, is a small glycoprotein belonging to the CC chemokine family. It is predominantly expressed by activated T cells, monocytes, and endothelial cells, and primarily acts as a chemoattractant for monocytes and T cells. CCL1 binds to the receptor CCR8, which is expressed on monocytes, neutrophils, and T cells, including within the thymus. This chemokine may perform dual functions: as an inflammatory chemokine during leukocyte migration into inflammatory sites and as a constitutive chemokine during T cell selection in the thymus. Furthermore, CCL1 has been associated with allergic inflammation and the recruitment of Th2 cells, suggesting a role in allergic diseases such as asthma.

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