Anticorps Recombinant de lapin anti-CCL14

CCL14 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

250487E9

N° de cat : 98554-1-PBS

Synonymes

C C motif chemokine 14, C-C motif chemokine 14, CCL-14, Chemokine CC-1/CC-3, HCC-1(1-74)

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Galerie de données de validation

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  FC experiment of Transfected CHO using 98554-1-RR (same clone as 98554-1-PBS)

  1x10^6 CHO cells or CCL14-transfected CHO cells were intracellularly stained with 0.25 ug Anti-Human CCL14 Rabbit RecAb (98554-1-RR, Clone:250487E9) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98554-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected CHO using 98554-1-RR (same clone as 98554-1-PBS)

  1x10^6 CHO cells or CCL14-transfected CHO cells were intracellularly stained with 0.25 ug Anti-Human CCL14 Rabbit RecAb (98554-1-RR, Clone:250487E9) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98554-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98554-1-PBS cible CCL14 dans les applications de FC (Intra) et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCL14 Protéine recombinante Eg2879
• Nom complet: chemokine (C-C motif) ligand 14
• Masse moléculaire calculée: 11k kDa
• Numéro d’acquisition GenBank: NM_032963.3
• Symbole du gène: CCL14
• Identification du gène (NCBI): 6358
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CCL14, also known as HCC-1, is a human plasma chemokine that belongs to the CC chemokine family. It was originally collected and purified from the hemofiltrate of patients with chronic renal failure. CCL14 is constitutively expressed in various tissues, including the spleen, bone marrow, liver, muscle, and intestine. CCL14 serves as a novel prognostic factor and tumor suppressor of HCC by modulating cell cycle and promoting apoptosis (PMID: 31641099), and CCL14 is a potential biomarker associated with immune cell infiltration in lung adenocarcinoma (PMID: 39030403).

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