Anticorps Polyclonal de lapin anti-CCL17/TARC

CCL17/TARC Polyclonal Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, ELISA

Conjugaison

Non conjugué

Publications(2)

N° de cat : 22342-1-AP

Synonymes

CCL17, TARC, CCL-17, CCL 17, C-C motif chemokine 17

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Galerie de données de validation

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  IHC staining of human colon using 22342-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22342-1-AP (CCL17 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human colon using 22342-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 22342-1-AP (CCL17 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human placenta using 22342-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 22342-1-AP (CCL17 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human placenta using 22342-1-AP

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 22342-1-AP (CCL17 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human colon cancer using 22342-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22342-1-AP (CCL17 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human colon cancer using 22342-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 22342-1-AP (CCL17 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en IHC: tissu de côlon humain, tissu de cancer du côlon humain, tissu placentaire humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Immunohistochimie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• IHC: See 2 publications below

Informations sur le produit

22342-1-AP cible CCL17/TARC dans les applications de IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CCL17/TARC Protéine recombinante Ag17832
• Nom complet: chemokine (C-C motif) ligand 17
• Masse moléculaire calculée: 94 aa, 11 kDa
• Numéro d’acquisition GenBank: BC112066
• Symbole du gène: CCL17
• Identification du gène (NCBI): 6361
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CCL17, also named as TARC, is a member of the CC chemokine family, and is highly expressed by thymus and other cells, including keratinocytes, endothelial cells, dendritic cells, bronchial epithelial cells and fibroblasts. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 induced chemotaxis and Ca2+ influx in the cells stably expressing CCR4, thereby demonstrating the ligand-receptor relationship between CCL17 and CCR4.

Publications

Species	Application	Title
human	IHC	Br J Haematol; Expression of multiple cytokines and chemokine receptor 4 in angioimmunoblastic T-cell lymphoma with abundant plasma cell infiltration involving the skin.; Authors - Shoko Nakayama
human	IHC	Hemasphere; NOTCH1 fusions in pediatric T-cell lymphoblastic lymphoma: A high-risk subgroup with CCL17 (TARC) levels as diagnostic biomarker; Authors - Emma Kroeze

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