Anticorps Recombinant de lapin anti-CCL20/MIP-3 alpha

CCL20/MIP-3 alpha Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241694B4

N° de cat : 84413-3-PBS

Synonymes

CCL20, MIP-3 Alpha, MIP-3α, 241694B4, Beta-chemokine exodus-1

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Galerie de données de validation

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  WB analysis using 84413-3-RR (same clone as 84413-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:2500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 84413-3-RR (same clone as 84413-3-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 84413-3-RR (CCL20/MIP-3 alpha antibody) at dilution of 1:2500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84413-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84413-3-PBS cible CCL20/MIP-3 alpha dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCL20/MIP-3 alpha Protéine recombinante Eg2398
• Nom complet: chemokine (C-C motif) ligand 20
• Masse moléculaire calculée: 11kDa
• Poids moléculaire observé: 11 kDa
• Numéro d’acquisition GenBank: NM_004591.3
• Symbole du gène: CCL20/MIP-3 alpha
• Identification du gène (NCBI): 6364
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17 (Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells (DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease (COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.

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