Anticorps Recombinant de lapin anti-CCL22/MDC
CCL22/MDC Recombinant Antibody for Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, souris
Applications
Indirect ELISA
Conjugaison
Non conjugué
CloneNo.
241668C10
N° de cat : 84370-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
84370-1-PBS cible CCL22/MDC dans les applications de Indirect ELISA et montre une réactivité avec des échantillons Humain, souris
| Réactivité | Humain, souris |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Recombinant |
| Type | Anticorps |
| Immunogène | CCL22/MDC Protéine recombinante Eg1974 |
| Nom complet | chemokine (C-C motif) ligand 22 |
| Masse moléculaire calculée | 93 aa, 11 kDa |
| Numéro d’acquisition GenBank | BC027952 |
| Symbole du gène | CCL22/MDC |
| Identification du gène (NCBI) | 6367 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine A |
| Tampon de stockage | PBS only |
| Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
CCL22, also known as macrophage-derived chemokine (MDC), is a member of the CC chemokine family. It is primarily produced by myeloid cells such as macrophages and dendritic cells (DCs) under steady-state conditions. CCL22 plays a significant role in immune responses by regulating the migration of different subsets of leukocytes. It shares the same receptor, CCR4, which is predominantly expressed by Th2 cells, making CCL22 a key mediator in the development of Th2-dominant diseases such as atopic dermatitis and asthma. Elevated serum levels of CCL22 are observed in patients with these conditions. CCL22 is also expressed in several types of tumor cells and Foxp3+ regulatory T cells (Tregs), suggesting its involvement in attracting Tregs into the tumor microenvironment to evade immune attacks.
