Anticorps Recombinant de lapin anti-CCL3/MIP-1 alpha

CCL3/MIP-1 alpha Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241695B10

N° de cat : 84701-1-PBS

Synonymes

241695B10, C-C motif chemokine 3, Ccl3, Heparin-binding chemotaxis protein, L2G25B

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Galerie de données de validation

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  IF Staining of RAW 264.7 using 84701-1-RR (same clone as 84701-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed RAW 264.7 cells using CCL3 antibody (84701-1-RR, Clone: 241695B10 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84701-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84701-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84701-1-RR against Mouse CCL3 were performed. The affinity constant is 4.00 nM.

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Informations sur le produit

84701-1-PBS cible CCL3/MIP-1 alpha dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCL3/MIP-1 alpha Protéine recombinante Eg2170
• Nom complet: chemokine (C-C motif) ligand 3
• Masse moléculaire calculée: 10kd
• Numéro d’acquisition GenBank: NM_011337
• Symbole du gène: Ccl3
• Identification du gène (NCBI): 20302
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCL3, also known as macrophage inflammatory protein-1 alpha (MIP-1α), is a chemokine that plays a significant role in immune responses. It is involved in recruiting immune cells, particularly monocytes and T cells, to sites of inflammation and infection. CCL3 is produced by various cell types, including activated macrophages and lymphocytes, and is crucial for orchestrating the immune response to infections and tissue injury. In summary, CCL3 is a multifunctional chemokine that is essential for immune cell recruitment and plays a role in various diseases, including chronic inflammatory conditions and cancer.

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