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Anticorps Polyclonal de lapin anti-CCL4/MIP-1 beta

CCL4/MIP-1 beta Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22352-1-PBS

Synonymes

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CCL4/MIP-1 beta Polyclonal antibody (22352-1-AP)

    WB analysis using 22352-1-AP (same clone as 22352-1-PBS)

    Untreated, PMA, LPS, and Brefeldin A treated THP-1 cells were subjected to SDS PAGE followed by western blot with 22352-1-AP (CCL4/MIP-1 beta antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22352-1-PBS in a different storage buffer formulation.

Informations sur le produit

22352-1-PBS cible CCL4/MIP-1 beta dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CCL4/MIP-1 beta Protéine recombinante Ag17928
Nom complet chemokine (C-C motif) ligand 4
Masse moléculaire calculée 92 aa, 10 kDa
Poids moléculaire observé11 kDa
Numéro d’acquisition GenBankBC107433
Symbole du gène CCL4/MIP-1 beta
Identification du gène (NCBI) 6351
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β), is a CC chemokine with specificity for CCR5 receptors, and is one of the major HIV-suppressive factors produced by CD8+ T-cells. MIP-1β is an acidic protein composed of 69 amino acids that is produced by many cells, particularly macrophages, dendritic cells, and lymphocytes. MIP-1β is responsible for the activation of PMN and is involved in acute neutrophilic inflammation. Recombinant MIP-1β induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

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