Anticorps Recombinant de lapin anti-CCL8/MCP-2

CCL8/MCP-2 Recombinant Antibody for FC (Intra)

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC (Intra)

Conjugaison

Non conjugué

CloneNo.

250174H6

N° de cat : 98480-1-PBS

Synonymes

Ccl8, C-C motif chemokine 8, Ccl 8, CCL-8, chemokine (C C motif) ligand 8

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98480-1-RR (same clone as 98480-1-PBS)

  1x10^6 HEK-293T cells (left) or CCL8/MCP-2-transfected HEK-293T cells (right) were intracellularly stained with 0.25 ug Anti-Mouse CCL8/MCP-2 Rabbit RecAb (98480-1-RR, Clone: 250174H6) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98480-1-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98480-1-RR (same clone as 98480-1-PBS)

  1x10^6 HEK-293T cells (left) or CCL8/MCP-2-transfected HEK-293T cells (right) were intracellularly stained with 0.25 ug Anti-Mouse CCL8/MCP-2 Rabbit RecAb (98480-1-RR, Clone: 250174H6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98480-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98480-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98480-1-RR against Mouse CCL8/MCP-2 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

98480-1-PBS cible CCL8/MCP-2 dans les applications de FC (Intra) et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCL8/MCP-2 Protéine recombinante Eg2771
• Nom complet: chemokine (C-C motif) ligand 8
• Masse moléculaire calculée: 11 kDa
• Numéro d’acquisition GenBank: NM_021443.3
• Symbole du gène: Ccl8
• Identification du gène (NCBI): 20307
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

The cys-cys (C-C) motif chemokine ligand 8 (CCL8, also known as MCP2) is implicated in various inflammatory processes. In bone marrow transplantation, circulating CCL8 levels positively correlate with the severity of graft-versus-host disease.

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