Anticorps Polyclonal de lapin anti-CCNB1IP1

CCNB1IP1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33150-1-PBS

Synonymes

C14orf18, Cyclin-B1-interacting protein 1, E3 ubiquitin-protein ligase CCNB1IP1, EC:2.3.2.27, HEI10

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Galerie de données de validation

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  WB analysis using 33150-1-AP (same clone as 33150-1-PBS)

  Rat kidney lysate was subjected to SDS PAGE followed by western blot with 33150-1-AP (CCNB1IP1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33150-1-PBS in a different storage buffer formulation.

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Informations sur le produit

33150-1-PBS cible CCNB1IP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CCNB1IP1 Protéine recombinante Ag38148
• Nom complet: cyclin B1 interacting protein 1
• Masse moléculaire calculée: 32 kDa
• Poids moléculaire observé: 32 kDa
• Numéro d’acquisition GenBank: BC004435
• Symbole du gène: CCNB1IP1
• Identification du gène (NCBI): 57820
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cyclin-B1-interacting protein 1 (CCNB1IP1) is an interacting protein of cyclin B1 involved in regulating cell cycle progression, and may be implicated in tumour events (PMID: 12612082). CCNB1IP1 modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Its overexpression causes delayed entry into mitosis (PMID: 12612082; 17297447). Additionally, CCNB1IP1 has been shown to stabilize the MYCN protein, which is a critical factor in neuroblastoma tumorigenesis (PMID: 37461251).

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