Anticorps Polyclonal de lapin anti-CCNL2

• Phare
• Validé par KD/KO

CCNL2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11212-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 11212-1-AP (same clone as 11212-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11212-1-AP (CCNL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11212-1-PBS in a different storage buffer formulation.

• 

  WB analysis of A375 using 11212-1-AP (same clone as 11212-1-PBS)

  WB result of CCNL2 antibody (11212-1-AP; 1:800; incubated at room temperature for 1.5 hours) with sh-Control and sh-CCNL2 transfected A375 cells. This data was developed using the same antibody clone with 11212-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

11212-1-PBS cible CCNL2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CCNL2 Protéine recombinante Ag1710
• Nom complet: cyclin L2
• Masse moléculaire calculée: 58 kDa
• Poids moléculaire observé: 28 kDa
• Numéro d’acquisition GenBank: BC016333
• Symbole du gène: CCNL2
• Identification du gène (NCBI): 81669
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCNL2 (Cyclin-L2) is also named as SB138 and Paneth cell-enhanced expression protein. Human cyclin L2 is a novel member of the cyclin family. Human cyclin L2 shares significant homology to cyclin L1, K, T1, T2, and C, which are involved in transcriptional regulation via phosphorylation of the C-terminal domain of RNA polymerase II (PMID: 14684736). Cyclin L2 co-localizes with splicing factors SC-35 and 9G8 within nuclear speckles and that it associates with hyperphosphorylated, but not hypophosphorylated, RNA polymerase II and CDK p110 PITSLRE kinase via its N-terminal cyclin domains (PMID: 14684736). Human cyclin L2 is expressed ubiquitously in normal human tissues and tumor cells.

{{ptg:RelatedPrimaryAntibodies}}