Anticorps Recombinant de lapin anti-CCR5

CCR5 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230266A6

N° de cat : 82942-1-PBS

Synonymes

C-C CKR-5, CC CKR 5, C-C chemokine receptor type 5, C C CKR 5, C C chemokine receptor type 5

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Galerie de données de validation

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  WB analysis using 82942-1-RR (same clone as 82942-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82942-1-RR (CCR5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82942-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82942-1-PBS

  Biolayer interferometry (BLl) kinetic assays of 82942-1-RR against Human CCR5 were performed. The affinity constant is 0.921 nM.

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Informations sur le produit

82942-1-PBS cible CCR5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CCR5 Protéine recombinante Ag11493
• Nom complet: chemokine (C-C motif) receptor 5
• Masse moléculaire calculée: 352 aa, 41 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC038398
• Symbole du gène: CCR5
• Identification du gène (NCBI): 1234
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CCR5 (also known as CD195) is a member of the beta chemokine receptor family. This protein is expressed by T cells and macrophages and is known to be an important co-receptor for macrophage-tropic viruses, including HIV, to enter host cells. The natural chemokine ligands that bind to CCR5 include MIP-1-alpha, MIP-1-beta, MCP-2, and RANTES.

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