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Anticorps Recombinant de lapin anti-CD100

CD100 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241709G4

N° de cat : 84465-5-PBS

Synonymes

SEMA4D, SEM4D, CD100 antigen, CD 100, A8

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of Daudi cells using CD100 Recombinant antibody (84465-5-RR)

    WB analysis of Daudi using 84465-5-RR (same clone as 84465-5-PBS)

    Daudi cells were subjected to SDS PAGE followed by western blot with 84465-5-RR (CD100 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84465-5-PBS in a different storage buffer formulation.

Informations sur le produit

84465-5-PBS cible CD100 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Masse moléculaire calculée 96 kDa
Poids moléculaire observé150 kDa
Numéro d’acquisition GenBankBC054500
Symbole du gène SEMA4D/CD100
Identification du gène (NCBI) 10507
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD100 (also known as SEMA4D), a 150 kDa homodimer, belongs to the family of immune semaphorins, and CD100 is abundantly expressed on resting T cells, NK cells, and antigen-presenting cells. As a transmembrane glycoprotein, it is digested to its soluble form, sCD100, by specific matrix metalloproteinases. CD100 has been reported that the expression levels of CD100, and one of its receptors, plexin-B1 (PLXNB1), are increased in head and neck, prostate, colon, breast, and lung cancers, and the interaction between them provides oncogenic signaling essential for tumor growth and metastasis.

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