Anticorps Monoclonal anti-CD106

CD106 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

FITC Fluorescent Dye

CloneNo.

1.G11B1

N° de cat : FITC-65049

Synonymes

CD106, DKFZp779G2333, INCAM 100, V CAM 1, VCAM 1, VCAM1



Applications testées

Résultats positifs en cytométriecellules HUVEC,

Dilution recommandée

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 10 µl per 10^6 cells in a 100 µl suspension or 10 µl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Applications publiées

FCSee 1 publications below

Informations sur le produit

FITC-65049 cible CD106 dans les applications de FC et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeHumain
Hôte / Isotype Mouse / IgG1, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène s/o
Nom complet vascular cell adhesion molecule 1
Masse moléculaire calculée 739 aa, 81 kDa
Numéro d’acquisition GenBankBC017276
Symbole du gène VCAM1
Identification du gène (NCBI) 7412
Conjugaison FITC Fluorescent Dye
Excitation/Emission maxima wavelengths498 nm / 526 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS avec azoture de sodium à 0,1 %.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).

Protocole

Product Specific Protocols
FC protocol for FITC CD106 antibody FITC-65049Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanFC

J Physiol Biochem

Hypoxia-induced CCL2/CCR2 axis in adipose-derived stem cells (ADSCs) promotes angiogenesis by human dermal microvascular endothelial cells (HDMECs) in flap tissues

Authors - Bairong Fang