Anticorps Recombinant de lapin anti-CD11a

CD11a Recombinant Antibody for FC

Hôte / Isotype

Rat / IgG2a

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

M17/4

N° de cat : 65670-1-PBS

Synonymes

Itgal, integrin alpha L, LFA 1

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Galerie de données de validation

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  FC experiment of mouse thymocytes using 65670-1-TR (same clone as 65670-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.5 ug Anti-Mouse CD11a (M17/4) Rat IgG2a RecAb (65670-1-TR, Clone:M17/4) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65670-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse thymocytes using 65670-1-TR (same clone as 65670-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.5 ug Anti-Mouse CD11a (M17/4) Rat IgG2a RecAb (65670-1-TR, Clone: M17/4) (red) or Rat IgG2a Isotype Control Recombinant Antibody (98427-1-TR, Clone: 250862A1) (blue), and FITC anti-Rat IgG2a antibody. Cells were not fixed. This data was developed using the same antibody clone with 65670-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65670-1-PBS cible CD11a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: integrin alpha L
• Numéro d’acquisition GenBank: BC145802
• Symbole du gène: CD11a
• Identification du gène (NCBI): 16408
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).

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