Anticorps Recombinant de lapin anti-CD11a

CD11a Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

TS2/4

N° de cat : Biotin-65563

Synonymes

Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, ITGAL, Integrin alpha-L, Integrin alpha L

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using Biotin-65563

  1x10^6 human peripheral blood leukocytes were unstained or surface stained with 0.25 ug Biotin Anti-Human CD11a (TS2/4) Mouse IgG2a RecAb (Biotin-65563, Clone: TS2/4) and CoraLite®488-conjugated streptavidin. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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  FC experiment of human peripheral blood leukocytes using Biotin-65563

  1x10^6 human peripheral blood leukocytes were unstained (blue) or surface stained with 5 ul Biotin Anti-Human CD11a (TS2/4) Mouse IgG2a RecAb (Biotin-65563, Clone: TS2/4) and CoraLite®488-conjugated streptavidin (red). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-65563 cible CD11a dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Lignée de CTL HLA-DR
• Nom complet: integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
• Masse moléculaire calculée: 129 kDa
• Numéro d’acquisition GenBank: BC008777
• Symbole du gène: CD11a
• Identification du gène (NCBI): 3683
• Conjugaison: Biotin
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).

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