Anticorps Monoclonal anti-CD11b

CD11b Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2b, kappa

Réactivité testée

Humain, souris

Applications

Conjugaison

PE-Cyanine7 Fluorescent Dye

CloneNo.

M1/70

N° de cat : PE-Cyanine7-65055

Synonymes

Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1



Informations sur le produit

PE-Cyanine7-65055 cible CD11b dans les applications de et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Rat / IgG2b, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Lymphocytes T spléniques de souris C57BL/10 et splénocytes C57BL/10 activés par la concanavaline A
Nom complet integrin alpha M
Masse moléculaire calculée127 kDa
Numéro d’acquisition GenBankBC156991
Symbole du gène CD11b
Identification du gène (NCBI) 16409
Conjugaison PE-Cyanine7 Fluorescent Dye
Excitation/Emission maxima wavelengths450-500 nm / 778 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

Protocole

Product Specific Protocols
FC protocol for PE-Cyanine7 CD11b antibody PE-Cyanine7-65055Download protocol
Standard Protocols
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